The signaling and selectivity of α‐adrenoceptor agonists for the human α2A, α2B and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors

α2‐adrenoceptors, (α2A, α2B and α2C‐subtypes), are Gi‐coupled receptors. Central activation of brain α2A and α2C‐adrenoceptors is the main site for α2‐agonist mediated clinical responses in hypertension, ADHD, muscle spasm and ITU management of sedation, reduction in opiate requirements, nausea and...

Descripción completa

Detalles Bibliográficos
Autores principales: Proudman, Richard G. W., Akinaga, Juliana, Baker, Jillian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471048/
https://www.ncbi.nlm.nih.gov/pubmed/36101495
http://dx.doi.org/10.1002/prp2.1003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471048/
https://www.ncbi.nlm.nih.gov/pubmed/36101495
http://dx.doi.org/10.1002/prp2.1003

Ejemplares similares