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Comprehensive analysis of TP53 and SPOP mutations and their impact on survival in metastatic prostate cancer

BACKGROUND: Although TP53 and SPOP are frequently mutated in metastatic prostate cancer (PCa), their prognostic value is ambiguous, and large sample studies are lacking, especially when they co-occur with other genetic alterations. METHODS: Genomic data and patients’ clinical characteristics in PCa...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Lai, Yiming, Peng, Shengmeng, Tang, Chen, Chen, Yongming, Li, Lingfeng, Huang, Hai, Guo, Zhenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471084/
https://www.ncbi.nlm.nih.gov/pubmed/36119488
http://dx.doi.org/10.3389/fonc.2022.957404