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Lipopolysaccharide sensitizes the therapeutic response of breast cancer to IAP antagonist

Inhibitor of apoptosis protein (IAP) is a class of E3 ubiquitin ligases functioning to support cancer survival and growth. Many small-molecule IAP antagonists have been developed, aiming to degrade IAP proteins to kill cancer. We have evaluated the effect of lipopolysaccharide (LPS), a component of...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Yao, Jimmy J., Chen, Zhongxuan, Lei, Wei, Duan, Rong, Yao, Zhenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471085/
https://www.ncbi.nlm.nih.gov/pubmed/36119107
http://dx.doi.org/10.3389/fimmu.2022.906357