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An open-label study evaluating the safety, behavioral, and electrophysiological outcomes of low-dose ketamine in children with ADNP syndrome

Activity-dependent neuroprotective protein (ADNP) syndrome is a rare genetic condition associated with intellectual disability and autism spectrum disorder. Preclinical evidence suggests that low-dose ketamine may induce expression of ADNP and that neuroprotective effects of ketamine may be mediated...

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Detalles Bibliográficos
Autores principales: Kolevzon, Alexander, Levy, Tess, Barkley, Sarah, Bedrosian-Sermone, Sandra, Davis, Matthew, Foss-Feig, Jennifer, Halpern, Danielle, Keller, Katherine, Kostic, Ana, Layton, Christina, Lee, Rebecca, Lerman, Bonnie, Might, Matthew, Sandin, Sven, Siper, Paige M., Sloofman, Laura G., Walker, Hannah, Zweifach, Jessica, Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471202/
https://www.ncbi.nlm.nih.gov/pubmed/36119806
http://dx.doi.org/10.1016/j.xhgg.2022.100138