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Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymphocytes

Current evidence highlights the critical role of the gut-kidney axis in the pathogenesis of IgA nephropathy (IgAN). However, few attempts have been made to explore targeted intestinal immunity therapy. This research aims to develop an oral intestine targeting medication based on extracellular vesicl...

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Detalles Bibliográficos
Autores principales: Zhang, Wang, Yuan, Ye, Li, Xiang, Luo, Jiao, Zhou, Zhanmei, Yu, Lei, Wang, Guobao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471245/
https://www.ncbi.nlm.nih.gov/pubmed/36119039
http://dx.doi.org/10.3389/fimmu.2022.900963