Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence

Chronic inflammation is widely observed in aging, but it is unclear whether extracellular vesicles (EVs) play a role in chronic disease-associated senescence. In our study, LC/MS profiling revealed that senescent cell derived EVs (SEN EVs) activate the immune response pathways of macrophages. Signif...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Yu, Liang, Jiaqi, Witwer, Kenneth W., Zhang, Ying, Wang, Qian, Yin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471260/
https://www.ncbi.nlm.nih.gov/pubmed/36119099
http://dx.doi.org/10.3389/fimmu.2022.955175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471260/
https://www.ncbi.nlm.nih.gov/pubmed/36119099
http://dx.doi.org/10.3389/fimmu.2022.955175

Ejemplares similares