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Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence

Chronic inflammation is widely observed in aging, but it is unclear whether extracellular vesicles (EVs) play a role in chronic disease-associated senescence. In our study, LC/MS profiling revealed that senescent cell derived EVs (SEN EVs) activate the immune response pathways of macrophages. Signif...

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Detalles Bibliográficos
Autores principales:	Xiao, Yu, Liang, Jiaqi, Witwer, Kenneth W., Zhang, Ying, Wang, Qian, Yin, Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471260/ https://www.ncbi.nlm.nih.gov/pubmed/36119099 http://dx.doi.org/10.3389/fimmu.2022.955175

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