Impact of queuosine modification of endogenous E. coli tRNAs on sense codon reassignment

The extent to which alteration of endogenous tRNA modifications may be exploited to improve genetic code expansion efforts has not been broadly investigated. Modifications of tRNAs are strongly conserved evolutionarily, but the vast majority of E. coli tRNA modifications are not essential. We identi...

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Detalles Bibliográficos
Autores principales: Tittle, Jillyn M., Schwark, David G., Biddle, Wil, Schmitt, Margaret A., Fisk, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471426/
https://www.ncbi.nlm.nih.gov/pubmed/36120552
http://dx.doi.org/10.3389/fmolb.2022.938114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471426/
https://www.ncbi.nlm.nih.gov/pubmed/36120552
http://dx.doi.org/10.3389/fmolb.2022.938114

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