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Poldip2 knockdown protects against lipopolysaccharide-induced acute lung injury via Nox4/Nrf2/NF-κB signaling pathway

Polymerase δ-interacting protein 2 (Poldip2) has been reported to mediate acute lung injury (ALI); however, the underlying mechanism is not fully explored. Male C57BL/6 mice and A549 cells were used to establish the lipopolysaccharide (LPS)-induced ALI model, then the expression of Poldip2 and its e...

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Detalles Bibliográficos
Autores principales: Wang, Yueguo, Wang, Wenwen, Zhou, Shusheng, Wang, Yulan, Cudjoe, Obed, Cha, Yu, Wang, Chunyan, Cao, Xiaoguang, Liu, Wei, Jin, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471427/
https://www.ncbi.nlm.nih.gov/pubmed/36120334
http://dx.doi.org/10.3389/fphar.2022.958916