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The nematode serotonin-gated chloride channel MOD-1: A novel target for anthelmintic therapy

Anthelmintics are used to treat human and veterinary parasitic diseases and to reduce crop and livestock production loss associated with parasitosis. The free-living nematode Caenorhabditis elegans, a model system for anthelmintic drug discovery, has a serotonin (5-HT)-gated chloride channel, MOD-1,...

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Detalles Bibliográficos
Autores principales: Rodriguez Araujo, Noelia, Hernando, Guillermina, Corradi, Jeremías, Bouzat, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471462/
https://www.ncbi.nlm.nih.gov/pubmed/35952761
http://dx.doi.org/10.1016/j.jbc.2022.102356