Cargando…
The nematode serotonin-gated chloride channel MOD-1: A novel target for anthelmintic therapy
Anthelmintics are used to treat human and veterinary parasitic diseases and to reduce crop and livestock production loss associated with parasitosis. The free-living nematode Caenorhabditis elegans, a model system for anthelmintic drug discovery, has a serotonin (5-HT)-gated chloride channel, MOD-1,...
Autores principales: | Rodriguez Araujo, Noelia, Hernando, Guillermina, Corradi, Jeremías, Bouzat, Cecilia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471462/ https://www.ncbi.nlm.nih.gov/pubmed/35952761 http://dx.doi.org/10.1016/j.jbc.2022.102356 |
Ejemplares similares
-
The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets
por: Wever, Claudia M., et al.
Publicado: (2015) -
Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity
por: Hernando, Guillermina, et al.
Publicado: (2019) -
A New Antagonist of Caenorhabditis elegans Glutamate-Activated Chloride Channels With Anthelmintic Activity
por: Castro, María Julia, et al.
Publicado: (2020) -
Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics
por: Lynagh, Timothy, et al.
Publicado: (2014) -
Advances in our understanding of nematode ion channels as potential anthelmintic targets
por: Choudhary, Shivani, et al.
Publicado: (2021)