The epigenetic impact of suberohydroxamic acid and 5-Aza-2′-deoxycytidine on DNMT3B expression in myeloma cell lines differing in IL-6 expression

Gene inactivation of the cyclin-dependent kinase inhibitors p16(INK4a), p15(INK4b) and p21(WAF) is frequently mediated by promoter gene methylation, whereas histone deacetylases (HDACs) control gene expression through their ability to deacetylate proteins. The effect of suberohydroxamic acid (SBHA)...

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Detalles Bibliográficos
Autores principales: Smesny Trtkova, Katerina, Luzna, Petra, Weiser Drozdkova, Denisa, Cizkova, Katerina, Janovska, Lucie, Gursky, Jan, Prukova, Dana, Frydrych, Ivo, Hajduch, Marian, Minarik, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471560/
https://www.ncbi.nlm.nih.gov/pubmed/36043519
http://dx.doi.org/10.3892/mmr.2022.12837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471560/
https://www.ncbi.nlm.nih.gov/pubmed/36043519
http://dx.doi.org/10.3892/mmr.2022.12837

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