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White matter disconnection and decreased functional connectivity between orbitofrontal cortex and the contralateral temporo-occipital cortex in adults with obsessive compulsive disorder

INTRODUCTION: Obsessive compulsive disorder (OCD) affects 2-3% of the general population. The neurobiology of OCD has been linked to dysfunction of cortico-striatal circuits connecting the orbitofrontal (OFC) to the striatum. Recently, this loop has become an approved target for non-invasive neuromo...

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Detalles Bibliográficos
Autores principales: Queiroz, J., Oliveira, J., Maia, A., Fonseca, C., Quendera, T., Oliveira-Maia, A., Barahona-Correa, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471806/
http://dx.doi.org/10.1192/j.eurpsy.2021.375