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Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression

Fibroblasts are widely distributed cells found in most tissues and upon tissue injury, they are able to differentiate into myofibroblasts, which express abundant extracellular matrix (ECM) proteins. Overexpression and unordered organization of ECM proteins cause tissue fibrosis in damaged tissue. Fi...

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Detalles Bibliográficos
Autores principales: Sun, Changye, Tian, Xiangqin, Jia, Yangyang, Yang, Mingming, Li, Yong, Fernig, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471990/
https://www.ncbi.nlm.nih.gov/pubmed/36102060
http://dx.doi.org/10.1098/rsob.210356