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Carboxymethyl chitosan prolongs adenovirus‐mediated expression of IL‐10 and ameliorates hepatic fibrosis in a mouse model

Effective and safe liver‐directed gene therapy has great promise in treating a broad range of liver diseases. While adenoviral (Ad) vectors have been widely used for efficacious in vivo gene delivery, their translational utilities are severely limited due to the short duration of transgene expressio...

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Detalles Bibliográficos
Autores principales: Gou, Yannian, Weng, Yaguang, Chen, Qian, Wu, Jinghong, Wang, Hao, Zhong, Jiamin, Bi, Yang, Cao, Daigui, Zhao, Piao, Dong, Xiangyu, Guo, Meichun, Wagstaff, William, Hendren‐Santiago, Bryce, Chen, Connie, Youssef, Andrew, Haydon, Rex C., Luu, Hue H., Reid, Russell R., Shen, Le, He, Tong‐Chuan, Fan, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472002/
https://www.ncbi.nlm.nih.gov/pubmed/36176604
http://dx.doi.org/10.1002/btm2.10306