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Targeted brain delivery of RVG29‐modified rifampicin‐loaded nanoparticles for Alzheimer's disease treatment and diagnosis

Alzheimer's disease (AD) is an aging‐related neurodegenerative disease. The main pathological features of AD are β‐amyloid protein (Aβ) deposition and tau protein hyperphosphorylation. Currently, there are no effective drugs for the etiological treatment of AD. Rifampicin (RIF) is a semi‐synthe...

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Detalles Bibliográficos
Autores principales: Zhou, Ruiyi, Zhu, Lihong, Zeng, Zhaohao, Luo, Rixin, Zhang, Jiawei, Guo, Rui, Zhang, Lei, Zhang, Qunying, Bi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472014/
https://www.ncbi.nlm.nih.gov/pubmed/36176608
http://dx.doi.org/10.1002/btm2.10395