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Targeted brain delivery of RVG29‐modified rifampicin‐loaded nanoparticles for Alzheimer's disease treatment and diagnosis
Alzheimer's disease (AD) is an aging‐related neurodegenerative disease. The main pathological features of AD are β‐amyloid protein (Aβ) deposition and tau protein hyperphosphorylation. Currently, there are no effective drugs for the etiological treatment of AD. Rifampicin (RIF) is a semi‐synthe...
Autores principales: | Zhou, Ruiyi, Zhu, Lihong, Zeng, Zhaohao, Luo, Rixin, Zhang, Jiawei, Guo, Rui, Zhang, Lei, Zhang, Qunying, Bi, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472014/ https://www.ncbi.nlm.nih.gov/pubmed/36176608 http://dx.doi.org/10.1002/btm2.10395 |
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