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LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization
BACKGROUND: Glioblastoma (GBM) is the most common malignant brain tumor with poor clinical outcomes. Immunotherapy has recently been an attractive and promising treatment of extracranial malignancies, however, most of clinical trials for GBM immunotherapy failed due to predominant accumulation of tu...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472135/ https://www.ncbi.nlm.nih.gov/pubmed/36096529 http://dx.doi.org/10.1136/jitc-2021-004452 |