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Peptide emulsions in incomplete Freund’s adjuvant create effective nurseries promoting egress of systemic CD4(+) and CD8(+) T cells for immunotherapy of cancer

Water-in-oil emulsion incomplete Freund’s adjuvant (IFA) has been used as an adjuvant in preventive and therapeutic vaccines since its development. New generation, highly purified modulations of the adjuvant, Montanide incomplete seppic adjuvant (ISA)-51 and Montanide ISA-720, were developed to redu...

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Detalles Bibliográficos
Autores principales: Melssen, Marit M, Fisher, Caroline T, Slingluff, Craig L, Melief, Cornelis J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472143/
https://www.ncbi.nlm.nih.gov/pubmed/36939214
http://dx.doi.org/10.1136/jitc-2022-004709