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A novel, robust method for quantification of multiple kynurenine pathway metabolites in the cerebrospinal fluid

AIM: Kynurenine metabolites are potential modulators of psychiatric disease. We aimed to develop a highly sensitive biochemical analysis of cerebrospinal fluid (CSF) tryptophan (TRP) metabolites, to investigate the stability of metabolites and to confirm our previous findings of aberrant CSF quinoli...

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Detalles Bibliográficos
Autores principales: Schwieler, Lilly, Trepci, Ada, Krzyzanowski, Stanislaw, Hermansson, Sigurd, Granqvist, Mathias, Piehl, Fredrik, Venckunas, Tomas, Brazaitis, Marius, Kamandulis, Sigitas, Lindqvist, Daniel, Jones, Arthur Daniel, Erhardt, Sophie, Brundin, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472175/
https://www.ncbi.nlm.nih.gov/pubmed/32209024
http://dx.doi.org/10.4155/bio-2019-0303