Cargando…

A novel, robust method for quantification of multiple kynurenine pathway metabolites in the cerebrospinal fluid

AIM: Kynurenine metabolites are potential modulators of psychiatric disease. We aimed to develop a highly sensitive biochemical analysis of cerebrospinal fluid (CSF) tryptophan (TRP) metabolites, to investigate the stability of metabolites and to confirm our previous findings of aberrant CSF quinoli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schwieler, Lilly, Trepci, Ada, Krzyzanowski, Stanislaw, Hermansson, Sigurd, Granqvist, Mathias, Piehl, Fredrik, Venckunas, Tomas, Brazaitis, Marius, Kamandulis, Sigitas, Lindqvist, Daniel, Jones, Arthur Daniel, Erhardt, Sophie, Brundin, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Newlands Press Ltd 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472175/ https://www.ncbi.nlm.nih.gov/pubmed/32209024 http://dx.doi.org/10.4155/bio-2019-0303

Ejemplares similares

Quantification of Plasma Kynurenine Metabolites Following One Bout of Sprint Interval Exercise
por: Trepci, Ada, et al.
Publicado: (2020)

Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects
por: Isung, Josef, et al.
Publicado: (2021)

Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans
por: Wyckelsma, Victoria L., et al.
Publicado: (2021)

Effect of Lower Body Compression Garments on Hemodynamics in Response to Running Session
por: Venckūnas, Tomas, et al.
Publicado: (2014)

Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance
por: Agudelo, Leandro Z., et al.
Publicado: (2019)

Carbohydrate restriction following strenuous glycogen-depleting exercise does not potentiate the acute molecular response associated with mitochondrial biogenesis in human skeletal muscle
por: Ramos, Catarina, et al.
Publicado: (2021)

Response to Three Weeks of Sprint Interval Training Cannot Be Explained by the Exertional Level
por: Krusnauskas, Raulas, et al.
Publicado: (2020)

Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial
por: Millischer, Vincent, et al.
Publicado: (2021)

Very Low Volume High-Intensity Interval Exercise Is More Effective in Young Than Old Women
por: Krusnauskas, Raulas, et al.
Publicado: (2018)

Adding High-Intensity Interval Training to Classical Resistance Training Does Not Impede the Recovery from Inactivity-Induced Leg Muscle Weakness
por: Venckunas, Tomas, et al.
Publicado: (2022)

One night of sleep deprivation impairs executive function but does not affect psychomotor or motor performance
por: Skurvydas, Albertas, et al.
Publicado: (2019)

Imbalanced Kynurenine Pathway in Schizophrenia
por: Kegel, Magdalena E, et al.
Publicado: (2014)

Lesions in the legs do not preclude ultra-marathon running for 100 days without pain: case report
por: Rutkauskas, Saulius, et al.
Publicado: (2019)

Physiological and Psychological Responses during Exercise and Recovery in a Cold Environment Is Gender-Related Rather Than Fabric-Related
por: Cernych, Margarita, et al.
Publicado: (2017)

Repeated Bout Effect Was More Expressed in Young Adult Males Than in Elderly Males and Boys
por: Gorianovas, Giedrius, et al.
Publicado: (2013)

Identification of cerebrospinal fluid and serum metabolomic biomarkers in first episode psychosis patients
por: Shang, Pei, et al.
Publicado: (2022)

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients
por: Schwieler, Lilly, et al.
Publicado: (2016)

The Kynurenine Pathway is Differentially Activated in Children with Lyme Disease and Tick-Borne Encephalitis
por: Wickström, Ronny, et al.
Publicado: (2021)

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria
por: Holmberg, Dag, et al.
Publicado: (2017)

Intratendinous Air Phenomenon: A New Ultrasound Marker of Tendon Damage?
por: Rutkauskas, Saulius, et al.
Publicado: (2017)

Response of Knee Extensor Muscle-Tendon Unit Stiffness to Unaccustomed and Repeated High-Volume Eccentric Exercise
por: Muanjai, Pornpimol, et al.
Publicado: (2021)

Moderate muscle cooling induced by single and intermittent/prolonged cold-water immersions differently affects muscle contractile function in young males
por: Treigyte, Viktorija, et al.
Publicado: (2023)

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
por: Brundin, L, et al.
Publicado: (2016)

Vitamin C and E Treatment Blunts Sprint Interval Training–Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans
por: Wyckelsma, Victoria L., et al.
Publicado: (2020)

Six autoantibodies associated with autoimmune encephalitis are not detectable in the cerebrospinal fluid of suicide attempters
por: Fernström, Johan, et al.
Publicado: (2017)

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration
por: Correia, Jorge C., et al.
Publicado: (2023)

Twin study shows association between monocyte chemoattractant protein-1 and kynurenic acid in cerebrospinal fluid
por: Johansson, Viktoria, et al.
Publicado: (2019)

Functional Impact of Post-exercise Cooling and Heating on Recovery and Training Adaptations: Application to Resistance, Endurance, and Sprint Exercise
por: Chaillou, Thomas, et al.
Publicado: (2022)

Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men
por: Hendrickse, Paul William, et al.
Publicado: (2021)

Chronic Antipsychotic Treatment in the Rat – Effects on Brain Interleukin-8 and Kynurenic Acid
por: Larsson, Markus K, et al.
Publicado: (2015)

Daily Resting Heart Rate Variability in Adolescent Swimmers during 11 Weeks of Training
por: Kamandulis, Sigitas, et al.
Publicado: (2020)

Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging
por: Solvang, Stein-Erik H., et al.
Publicado: (2022)

Cerebrospinal Fluid Neurofilament Light Chain Is Associated with Kynurenine Pathway Metabolite Changes in Multiple Sclerosis
por: Rajda, Cecilia, et al.
Publicado: (2020)

Sustained Elevation of Kynurenic Acid in the Cerebrospinal Fluid of Patients with Herpes Simplex Virus Type 1 Encephalitis
por: Atlas, Ann, et al.
Publicado: (2013)

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease
por: Rodrigues, Filipe B., et al.
Publicado: (2021)

Intense Inflammation and Nerve Damage in Early Multiple Sclerosis Subsides at Older Age: A Reflection by Cerebrospinal Fluid Biomarkers
por: Khademi, Mohsen, et al.
Publicado: (2013)

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia
por: Gracias, Jessica, et al.
Publicado: (2022)

Cognitive impairments correlate with increased central nervous system immune activation after allogeneic haematopoietic stem cell transplantation
por: Boberg, Erik, et al.
Publicado: (2023)

Associations between Muscle-Tendon Morphology and Functional Movements Capacity, Flexibility, and Balance in Older Women
por: Muanjai, Pornpimol, et al.
Publicado: (2022)

Riding a Mechanical Scooter from the Inconvenient Side Promotes Muscular Balance Development in Children
por: Mickevicius, Mantas, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rrsld8ed3d2n3r0m5pqef2m3gm