Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture

Hydroxychloroquine (HCQ), a drug used to treat lupus and malaria, was proposed as a treatment for SARS-coronavirus-2 (SARS-CoV-2) infection, albeit with controversy. In vitro, HCQ effectively inhibits viral entry, but its use in the clinic has been hampered by conflicting results. A better understan...

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Detalles Bibliográficos
Autores principales: Yuan, Zixuan, Pavel, Mahmud Arif, Wang, Hao, Kwachukwu, Jerome C., Mediouni, Sonia, Jablonski, Joseph Anthony, Nettles, Kendall W., Reddy, Chakravarthy B., Valente, Susana T., Hansen, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472185/
https://www.ncbi.nlm.nih.gov/pubmed/36104427
http://dx.doi.org/10.1038/s42003-022-03841-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472185/
https://www.ncbi.nlm.nih.gov/pubmed/36104427
http://dx.doi.org/10.1038/s42003-022-03841-8

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