N-cadherin protects oral cancer cells from NK cell killing in the circulation by inducing NK cell functional exhaustion via the KLRG1 receptor

BACKGROUND: Circulating tumor cells (CTCs) can survive in the circulation and return to primary tumors through a self-seeding process. However, the mechanisms underlying CTCs escape from natural killer (NK) cell-mediated immune surveillance remain unclear. METHOD: Self-seeded tumor cells were isolat...

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Detalles Bibliográficos
Autores principales: Lou, Chao, Wu, Kailiu, Shi, Jianbo, Dai, Zhenlin, Xu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472211/
https://www.ncbi.nlm.nih.gov/pubmed/36096526
http://dx.doi.org/10.1136/jitc-2022-005061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472211/
https://www.ncbi.nlm.nih.gov/pubmed/36096526
http://dx.doi.org/10.1136/jitc-2022-005061

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