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Toward the Next Generation of Spine Bioreactors: Validation of an Ex Vivo Intervertebral Disc Organ Model and Customized Specimen Holder for Multiaxial Loading

[Image: see text] A new generation of bioreactors with integrated six degrees of freedom (6 DOF) aims to mimic more accurately the natural intervertebral disc (IVD) load. We developed and validated in a biological and mechanical study a specimen holder and corresponding ex vivo IVD organ model accor...

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Detalles Bibliográficos
Autores principales: Šećerović, Amra, Ristaniemi, Aapo, Cui, Shangbin, Li, Zhen, Soubrier, Astrid, Alini, Mauro, Ferguson, Stephen J, Weder, Gilles, Heub, Sarah, Ledroit, Diane, Grad, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472220/
https://www.ncbi.nlm.nih.gov/pubmed/35977717
http://dx.doi.org/10.1021/acsbiomaterials.2c00330