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Toward the Next Generation of Spine Bioreactors: Validation of an Ex Vivo Intervertebral Disc Organ Model and Customized Specimen Holder for Multiaxial Loading
[Image: see text] A new generation of bioreactors with integrated six degrees of freedom (6 DOF) aims to mimic more accurately the natural intervertebral disc (IVD) load. We developed and validated in a biological and mechanical study a specimen holder and corresponding ex vivo IVD organ model accor...
Autores principales: | Šećerović, Amra, Ristaniemi, Aapo, Cui, Shangbin, Li, Zhen, Soubrier, Astrid, Alini, Mauro, Ferguson, Stephen J, Weder, Gilles, Heub, Sarah, Ledroit, Diane, Grad, Sibylle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472220/ https://www.ncbi.nlm.nih.gov/pubmed/35977717 http://dx.doi.org/10.1021/acsbiomaterials.2c00330 |
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