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Generation of 3D Spheroids Using a Thiol–Acrylate Hydrogel Scaffold to Study Endocrine Response in ER(+) Breast Cancer

[Image: see text] Culturing cancer cells in a three-dimensional (3D) environment better recapitulates in vivo conditions by mimicking cell-to-cell interactions and mass transfer limitations of metabolites, oxygen, and drugs. Recent drug studies have suggested that a high rate of preclinical and clin...

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Detalles Bibliográficos
Autores principales: Khan, Anowar H., Zhou, Sophia P., Moe, Margaret, Ortega Quesada, Braulio A., Bajgiran, Khashayar R., Lassiter, Haley R., Dorman, James A., Martin, Elizabeth C., Pojman, John A., Melvin, Adam T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472224/
https://www.ncbi.nlm.nih.gov/pubmed/36001134
http://dx.doi.org/10.1021/acsbiomaterials.2c00491