An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry

[Image: see text] The characterization of therapeutic glycoproteins is challenging due to the structural heterogeneity of the therapeutic protein glycosylation. This study presents an in-depth analytical strategy for glycosylation of first-generation erythropoietin (epoetin beta), including a develo...

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Detalles Bibliográficos
Autores principales: Guan, Yudong, Zhang, Min, Gaikwad, Manasi, Voss, Hannah, Fazel, Ramin, Ansari, Samira, Shen, Huali, Wang, Jigang, Schlüter, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472269/
https://www.ncbi.nlm.nih.gov/pubmed/34110173
http://dx.doi.org/10.1021/acs.jproteome.1c00221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472269/
https://www.ncbi.nlm.nih.gov/pubmed/34110173
http://dx.doi.org/10.1021/acs.jproteome.1c00221

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