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Poly-Gly Region Regulates the Accessibility of Metal Binding Sites in Snake Venom Peptides

[Image: see text] It is supposed that the presence of poly-His regions in close proximity to poly-Gly domains in snake venoms is related to their biological activity; poly-His/poly-Gly (pHpG) peptides inhibit the activity of metalloproteinases during venom storage via the chelation metal ions, neces...

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Detalles Bibliográficos
Autores principales: Wa̧tły, Joanna, Hecel, Aleksandra, Wieczorek, Robert, Rowińska-Żyrek, Magdalena, Kozłowski, Henryk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472272/
https://www.ncbi.nlm.nih.gov/pubmed/36039984
http://dx.doi.org/10.1021/acs.inorgchem.2c02584