CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair

A critical determinant of DNA repair pathway choice is REV7, an adaptor that binds to various DNA repair proteins through its C-terminal seatbelt domain. The REV7 seatbelt binds to either REV3, activating translesion synthesis, or to SHLD3, activating non-homologous end joining (NHEJ) repair. Recent...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Feng, Sarangi, Prabha, Iyer, Divya Ramalingam, Feng, Hanrong, Moreau, Lisa, Nguyen, Huy, Clairmont, Connor, D’Andrea, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472291/
https://www.ncbi.nlm.nih.gov/pubmed/36044844
http://dx.doi.org/10.1016/j.celrep.2022.111297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472291/
https://www.ncbi.nlm.nih.gov/pubmed/36044844
http://dx.doi.org/10.1016/j.celrep.2022.111297

Ejemplares similares