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CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair

A critical determinant of DNA repair pathway choice is REV7, an adaptor that binds to various DNA repair proteins through its C-terminal seatbelt domain. The REV7 seatbelt binds to either REV3, activating translesion synthesis, or to SHLD3, activating non-homologous end joining (NHEJ) repair. Recent...

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Detalles Bibliográficos
Autores principales:	Li, Feng, Sarangi, Prabha, Iyer, Divya Ramalingam, Feng, Hanrong, Moreau, Lisa, Nguyen, Huy, Clairmont, Connor, D’Andrea, Alan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472291/ https://www.ncbi.nlm.nih.gov/pubmed/36044844 http://dx.doi.org/10.1016/j.celrep.2022.111297

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