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IL-37 protects against airway remodeling by reversing bronchial epithelial–mesenchymal transition via IL-24 signaling pathway in chronic asthma

BACKGROUND: Epithelial–mesenchymal transition (EMT) is one of the mechanisms of airway remodeling in chronic asthma. Interleukin (IL)-24 has been implicated in the promotion of tissue fibrosis, and increased IL-24 levels have been observed in the nasal secretions and sputum of asthmatic patients. Ho...

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Detalles Bibliográficos
Autores principales: Feng, Kang-ni, Meng, Ping, Zou, Xiao-ling, Zhang, Min, Li, Hai-ke, Yang, Hai-ling, Li, Hong-tao, Zhang, Tian-tuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472332/
https://www.ncbi.nlm.nih.gov/pubmed/36100847
http://dx.doi.org/10.1186/s12931-022-02167-7