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Pattern matching for high precision detection of LINE-1s in human genomes

BACKGROUND: Long interspersed element 1 (LINE-1 or L1) retrotransposons are mobile elements that constitute 17–20% of the human genome. Strong correlations between abnormal L1 expression and several human diseases have been reported. This has motivated increasing interest in accurate quantification...

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Detalles Bibliográficos
Autores principales: Lopez, Juan O., Seguel, Jaime, Chamorro, Andres, Ramos, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472350/
https://www.ncbi.nlm.nih.gov/pubmed/36100885
http://dx.doi.org/10.1186/s12859-022-04907-4