Dexmedetomidine reduces myocardial ischemia-reperfusion injury in young mice through MIF/AMPK/GLUT4 axis

BACKGROUND: Reperfusion of ischemic tissue has adverse impact on the myocardium. Dexmedetomidine (Dex) is a α2-adrenergic receptor (α2-AR) agonist with sedative and analgesic effects. Macrophage migration inhibition factor (MIF) is a pressure-regulating cytokine and is responsible for inflammatory a...

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Detalles Bibliográficos
Autores principales: Chen, Siyu, Li, Aimei, Wu, Jianjiang, Huang, Yidan, Zou, Tiantian, Tailaiti, Taiwangu, Wang, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472426/
https://www.ncbi.nlm.nih.gov/pubmed/36104681
http://dx.doi.org/10.1186/s12871-022-01825-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472426/
https://www.ncbi.nlm.nih.gov/pubmed/36104681
http://dx.doi.org/10.1186/s12871-022-01825-z

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