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RBM45 is an m(6)A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs

N(6)-methyladenosine (m(6)A) is deposited co-transcriptionally on thousands of cellular mRNAs and plays important roles in mRNA processing and cellular function. m(6)A is particularly abundant within the brain and is critical for neurodevelopment. However, the mechanisms through which m(6)A contribu...

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Detalles Bibliográficos
Autores principales: Choi, Seung H., Flamand, Mathieu N., Liu, Bei, Zhu, Huanyu, Hu, Meghan, Wang, Melanie, Sewell, Jonathon, Holley, Christopher L., Al-Hashimi, Hashim M., Meyer, Kate D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472474/
https://www.ncbi.nlm.nih.gov/pubmed/36044854
http://dx.doi.org/10.1016/j.celrep.2022.111293