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XAF1 Protects Host against Emerging RNA Viruses by Stabilizing IRF1-Dependent Antiviral Immunity

XIAP-associated factor 1 (XAF1) is an interferon (IFN)-stimulated gene (ISG) that enhances IFN-induced apoptosis. However, it is unexplored whether XAF1 is essential for the host fighting against invaded viruses. Here, we find that XAF1 is significantly upregulated in the host cells infected with em...

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Detalles Bibliográficos
Autores principales: Han, Yu, Bai, Xue, Liu, Siying, Zhu, Jingfei, Zhang, Fan, Xie, Lifen, Liu, Guodi, Jiang, Xiaohui, Zhang, Mingchao, Huang, Yingkang, Wang, Jingfeng, Li, Dapei, Zhang, Huiying, He, Yuanqing, He, Sudan, Xia, Yu, Xu, Xiulong, Xu, Feng, Ma, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472610/
https://www.ncbi.nlm.nih.gov/pubmed/35972291
http://dx.doi.org/10.1128/jvi.00774-22