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Herpes Simplex Virus 1 Can Bypass Impaired Epidermal Barriers upon Ex Vivo Infection of Skin from Atopic Dermatitis Patients

To infect its human host, herpes simplex virus 1 (HSV-1) must overcome the protective barriers of skin and mucosa. Here, we addressed whether pathological skin conditions can facilitate viral entry via the skin surface and used ex vivo infection studies to explore viral invasion in atopic dermatitis...

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Detalles Bibliográficos
Autores principales: Möckel, Maureen, De La Cruz, Nydia C., Rübsam, Matthias, Wirtz, Lisa, Tantcheva-Poor, Iliana, Malter, Wolfram, Zinser, Max, Bieber, Thomas, Knebel-Mörsdorf, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472615/
https://www.ncbi.nlm.nih.gov/pubmed/35969080
http://dx.doi.org/10.1128/jvi.00864-22