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African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation

African swine fever virus (ASFV) is the etiological agent of a highly lethal hemorrhagic disease in domestic pigs and wild boars that has significant economic consequences for the pig industry. The type I interferon (IFN) signaling pathway is a pivotal component of the innate antiviral response, and...

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Detalles Bibliográficos
Autores principales: Li, Liang, Fu, Jiyang, Li, Jixuan, Guo, Shibang, Chen, Qichao, Zhang, Yibo, Liu, Zhankui, Tan, Chen, Chen, Huanchun, Wang, Xiangru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472647/
https://www.ncbi.nlm.nih.gov/pubmed/35972295
http://dx.doi.org/10.1128/jvi.00944-22