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Modern Solutions for Ancient Pathogens: Direct Pathogen Sequencing for Diagnosis of Lepromatous Leprosy and Cerebral Coenurosis

Microbes unculturable in vitro remain diagnostically challenging, dependent historically on clinical findings, histology, or targeted molecular detection. We applied whole-genome sequencing directly from tissue to diagnose infections with mycobacteria (leprosy) and parasites (coenurosis). Direct pat...

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Detalles Bibliográficos
Autores principales: Young, Bernadette C, Bush, Stephen J, Lipworth, Sam, George, Sophie, Dingle, Kate E, Sanderson, Nick, Brankin, Alice, Walker, Timothy, Sharma, Srilakshmi, Leong, James, Plaha, Puneet, Hofer, Monika, Chiodini, Peter, Gottstein, B, Furrer, Lavinia, Crook, Derrick, Brent, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472670/
https://www.ncbi.nlm.nih.gov/pubmed/36119959
http://dx.doi.org/10.1093/ofid/ofac428