An orally administered drug prevents selection for antibiotic-resistant bacteria in the gut during daptomycin therapy

BACKGROUND AND OBJECTIVES: Previously, we showed proof-of-concept in a mouse model that oral administration of cholestyramine prevented enrichment of daptomycin-resistant Enterococcus faecium in the gastrointestinal (GI) tract during daptomycin therapy. Cholestyramine binds daptomycin in the gut, wh...

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Detalles Bibliográficos
Autores principales: Morley, Valerie J, Sim, Derek G, Penkevich, Aline, Woods, Robert J, Read, Andrew F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472784/
https://www.ncbi.nlm.nih.gov/pubmed/36118914
http://dx.doi.org/10.1093/emph/eoac035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472784/
https://www.ncbi.nlm.nih.gov/pubmed/36118914
http://dx.doi.org/10.1093/emph/eoac035

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