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An orally administered drug prevents selection for antibiotic-resistant bacteria in the gut during daptomycin therapy

BACKGROUND AND OBJECTIVES: Previously, we showed proof-of-concept in a mouse model that oral administration of cholestyramine prevented enrichment of daptomycin-resistant Enterococcus faecium in the gastrointestinal (GI) tract during daptomycin therapy. Cholestyramine binds daptomycin in the gut, wh...

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Detalles Bibliográficos
Autores principales:	Morley, Valerie J, Sim, Derek G, Penkevich, Aline, Woods, Robert J, Read, Andrew F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472784/ https://www.ncbi.nlm.nih.gov/pubmed/36118914 http://dx.doi.org/10.1093/emph/eoac035

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