Vascular senescence in progeria: role of endothelial dysfunction

AIMS: Hutchinson–Gilford progeria syndrome (HGPS) is a pre-mature aging disorder caused by the mutation of the LMNA gene leading to an irreversibly farnesylated lamin A protein: progerin. The major causes of death in HGPS are coronary and arterial occlusive disease. In the murine model of HGPS, vasc...

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Detalles Bibliográficos
Autores principales: Xu, Qiu, Mojiri, Anahita, Boulahouache, Luay, Morales, Elisa, Walther, Brandon K, Cooke, John P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472787/
https://www.ncbi.nlm.nih.gov/pubmed/36117952
http://dx.doi.org/10.1093/ehjopen/oeac047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472787/
https://www.ncbi.nlm.nih.gov/pubmed/36117952
http://dx.doi.org/10.1093/ehjopen/oeac047

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