Cargando…

Vascular senescence in progeria: role of endothelial dysfunction

AIMS: Hutchinson–Gilford progeria syndrome (HGPS) is a pre-mature aging disorder caused by the mutation of the LMNA gene leading to an irreversibly farnesylated lamin A protein: progerin. The major causes of death in HGPS are coronary and arterial occlusive disease. In the murine model of HGPS, vasc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Qiu, Mojiri, Anahita, Boulahouache, Luay, Morales, Elisa, Walther, Brandon K, Cooke, John P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472787/ https://www.ncbi.nlm.nih.gov/pubmed/36117952 http://dx.doi.org/10.1093/ehjopen/oeac047

Ejemplares similares

Caveats on modeling of nuclear biomechanics
por: Walther, Brandon K., et al.
Publicado: (2020)

Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020)

Publisher Correction: Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020)

Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria
por: Manakanatas, Christina, et al.
Publicado: (2022)

Dedifferentiation rescues senescence of progeria cells but only while pluripotent
por: Niedernhofer, Laura J, et al.
Publicado: (2011)

DRG2 Depletion Promotes Endothelial Cell Senescence and Vascular Endothelial Dysfunction
por: Le, Anh-Nhung, et al.
Publicado: (2022)

Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome
por: Mu, Xiaodong, et al.
Publicado: (2020)

Metabolic Dysfunction in Hutchinson–Gilford Progeria Syndrome
por: Kreienkamp, Ray, et al.
Publicado: (2020)

Progeria
Publicado: (1935)

Role of MicroRNAs in acceleration of vascular endothelial senescence
por: Toyama, Kensuke, et al.
Publicado: (2022)

Erythrocyte Senescence in a Model of Rat Displaying Hutchinson-Gilford Progeria Syndrome
por: Chaudhary, Manoj Kumar, et al.
Publicado: (2018)

Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
por: Bloom, Samuel I., et al.
Publicado: (2023)

Living with Progeria
por: Stamsnijder, Marjet
Publicado: (2010)

Nucleolar and Ribosomal Dysfunction—A Common Pathomechanism in Childhood Progerias?
por: Phan, Tamara, et al.
Publicado: (2019)

Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells
por: Huo, Jia, et al.
Publicado: (2018)

Mechanisms of angiogenic incompetence in Hutchinson–Gilford progeria via downregulation of endothelial NOS
por: Gete, Yantenew G., et al.
Publicado: (2021)

The Effect of Type of Delivery on the Nitric Oxide Metabolites and Endothelial Dysfunction in Pregnant Women
por: Mojiri, Maedeh, et al.
Publicado: (2020)

Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis
por: Di Pasquale, Elisa, et al.
Publicado: (2019)

Nuclear Pore Complexes Cluster in Dysmorphic Nuclei of Normal and Progeria Cells during Replicative Senescence
por: Röhrl, Jennifer M., et al.
Publicado: (2021)

A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
por: Chen, Xue, et al.
Publicado: (2021)

Arterial stiffness and cardiac dysfunction in Hutchinson–Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase
por: von Kleeck, Ryan, et al.
Publicado: (2021)

Redox theory in progeria
por: Villa-Bellosta, Ricardo
Publicado: (2020)

New treatments for progeria
por: Villa-Bellosta, Ricardo
Publicado: (2019)

The pursuit of therapy for progeria
por: Saxena, Saurabh, et al.
Publicado: (2021)

Significance of neutrophil microparticles in ischaemia‐reperfusion: Pro‐inflammatory effectors of endothelial senescence and vascular dysfunction
por: El Habhab, Ali, et al.
Publicado: (2020)

Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
por: Bersini, Simone, et al.
Publicado: (2020)

Vascular Dysfunction in Malaria: Understanding the Role of the Endothelial Glycocalyx
por: Bush, Margaret A., et al.
Publicado: (2021)

Werner's Syndrome (Progeria in the Adult)
por: Grant, Alan P.
Publicado: (1957)

Hutchinson-Gilford progeria syndrome
por: Bhukya, Amar Singh, et al.
Publicado: (2015)

Linking In Vitro Models of Endothelial Dysfunction with Cell Senescence
por: Jimenez Trinidad, Francisco R., et al.
Publicado: (2021)

Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells
por: Stabenow, Leonie K., et al.
Publicado: (2022)

PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome
por: Wang, Ming, et al.
Publicado: (2020)

Targeting RAS‐converting enzyme 1 overcomes senescence and improves progeria‐like phenotypes of ZMPSTE24 deficiency
por: Yao, Haidong, et al.
Publicado: (2020)

Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson–Gilford progeria (HGPS)
por: Dreesen, Oliver
Publicado: (2020)

Lysophosphatidic acid receptor LPA(3) prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome
por: Chen, Wei‐Min, et al.
Publicado: (2019)

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells
por: Aveleira, Célia A, et al.
Publicado: (2020)

Anti‐hsa‐miR‐59 alleviates premature senescence associated with Hutchinson‐Gilford progeria syndrome in mice
por: Hu, Qianying, et al.
Publicado: (2022)

Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells
por: Liu, Lei, et al.
Publicado: (2022)

The role of oxidative stress in diabetes mellitus-induced vascular endothelial dysfunction
por: An, Ying, et al.
Publicado: (2023)

Protective Role of Antioxidant Huskless Barley Extracts on TNF-α-Induced Endothelial Dysfunction in Human Vascular Endothelial Cells
por: Liao, Zhanghua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ie8524fsukh61gqmo297bn41uv