Structural and Dynamic Effects of PTEN C-Terminal Tail Phosphorylation

[Image: see text] The phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor gene encodes a tightly regulated dual-specificity phosphatase that serves as the master regulator of PI3K/AKT/mTOR signaling. The carboxy-terminal tail (CTT) is key to regulation and harbors multi...

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Detalles Bibliográficos
Autores principales: Smith, Iris N., Dawson, Jennifer E., Krieger, James, Thacker, Stetson, Bahar, Ivet, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472802/
https://www.ncbi.nlm.nih.gov/pubmed/36001481
http://dx.doi.org/10.1021/acs.jcim.2c00441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472802/
https://www.ncbi.nlm.nih.gov/pubmed/36001481
http://dx.doi.org/10.1021/acs.jcim.2c00441

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