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Structural and Dynamic Effects of PTEN C-Terminal Tail Phosphorylation

[Image: see text] The phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor gene encodes a tightly regulated dual-specificity phosphatase that serves as the master regulator of PI3K/AKT/mTOR signaling. The carboxy-terminal tail (CTT) is key to regulation and harbors multi...

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Detalles Bibliográficos
Autores principales:	Smith, Iris N., Dawson, Jennifer E., Krieger, James, Thacker, Stetson, Bahar, Ivet, Eng, Charis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472802/ https://www.ncbi.nlm.nih.gov/pubmed/36001481 http://dx.doi.org/10.1021/acs.jcim.2c00441

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