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Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients

INTRODUCTION: BRCA1 and BRCA2 germline pathogenic variants (GPVs) account for most of the 5-10% of breast cancer (BC) that is attributable to inherited genetic variants. BRCA1 GPVs are associated with the triple negative subtype, whereas BRCA2 GPVs are likely to result in higher grade, estrogen-rece...

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Detalles Bibliográficos
Autores principales: Paixão, Daniele, Torrezan, Giovana Tardin, Santiago, Karina Miranda, Formiga, Maria Nirvana, Ahuno, Samuel Terkper, Dias-Neto, Emmanuel, Tojal da Silva, Israel, Foulkes, William D., Polak, Paz, Carraro, Dirce Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472814/
https://www.ncbi.nlm.nih.gov/pubmed/36119527
http://dx.doi.org/10.3389/fonc.2022.976959