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Qishen Granule Protects against Doxorubicin-Induced Cardiotoxicity by Coordinating MDM2-p53-Mediated Mitophagy and Mitochondrial Biogenesis

Doxorubicin (DOX), the anthracycline chemotherapeutic agent, is widely used for the treatment of various cancers. However, its clinical application is compromised by dose-dependent and fatal cardiotoxicity. This study is aimed at investigating the cardioprotective effects of Qishen granule (QSG) and...

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Detalles Bibliográficos
Autores principales: Li, Weili, Zhang, Yawen, Wang, Xiaoping, Cao, Jing, Qian, Weina, Ling, Guanjing, Tan, Nannan, Jiang, Jinchi, Sun, Qianbin, Li, Chun, Wang, Wei, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473341/
https://www.ncbi.nlm.nih.gov/pubmed/36120600
http://dx.doi.org/10.1155/2022/4344677