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Qishen Granule Protects against Doxorubicin-Induced Cardiotoxicity by Coordinating MDM2-p53-Mediated Mitophagy and Mitochondrial Biogenesis
Doxorubicin (DOX), the anthracycline chemotherapeutic agent, is widely used for the treatment of various cancers. However, its clinical application is compromised by dose-dependent and fatal cardiotoxicity. This study is aimed at investigating the cardioprotective effects of Qishen granule (QSG) and...
Autores principales: | Li, Weili, Zhang, Yawen, Wang, Xiaoping, Cao, Jing, Qian, Weina, Ling, Guanjing, Tan, Nannan, Jiang, Jinchi, Sun, Qianbin, Li, Chun, Wang, Wei, Wang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473341/ https://www.ncbi.nlm.nih.gov/pubmed/36120600 http://dx.doi.org/10.1155/2022/4344677 |
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