In situ monitoring of functional activity of extracellular matrix stiffness-dependent multidrug resistance protein 1 using scanning electrochemical microscopy

Extracellular matrix (ECM) stiffness affects the drug resistance behavior of cancer cells, while multidrug resistance protein 1 (MRP1) on the cell membrane confers treatment resistance via actively transporting drugs out of cancer cells. However, the relationship between ECM stiffness and MRP1 funct...

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Detalles Bibliográficos
Autores principales: Kuermanbayi, Shuake, Yang, Yaowei, Zhao, Yuxiang, Li, Yabei, Wang, Le, Yang, Jin, Zhou, Yan, Xu, Feng, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473519/
https://www.ncbi.nlm.nih.gov/pubmed/36277620
http://dx.doi.org/10.1039/d2sc02708a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473519/
https://www.ncbi.nlm.nih.gov/pubmed/36277620
http://dx.doi.org/10.1039/d2sc02708a

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