Uncovering the molecular mechanism for dual effect of ATP on phase separation in FUS solution

Recent studies reported that adenosine triphosphate (ATP) could inhibit and enhance the phase separation in prion-like proteins. The molecular mechanism underlying such a puzzling phenomenon remains elusive. Here, taking the fused in sarcoma (FUS) solution as an example, we comprehensively reveal th...

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Detalles Bibliográficos
Autores principales: Ren, Chun-Lai, Shan, Yue, Zhang, Pengfei, Ding, Hong-Ming, Ma, Yu-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Physical and Materials Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473584/
https://www.ncbi.nlm.nih.gov/pubmed/36103543
http://dx.doi.org/10.1126/sciadv.abo7885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473584/
https://www.ncbi.nlm.nih.gov/pubmed/36103543
http://dx.doi.org/10.1126/sciadv.abo7885

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