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An AMPK phosphoregulated RhoGEF feedback loop tunes cortical flow–driven amoeboid migration in vivo

Development, morphogenesis, immune system function, and cancer metastasis rely on the ability of cells to move through diverse tissues. To dissect migratory cell behavior in vivo, we developed cell type–specific imaging and perturbation techniques for Drosophila primordial germ cells (PGCs). We find...

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Detalles Bibliográficos
Autores principales: Lin, Benjamin, Luo, Jonathan, Lehmann, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473612/
https://www.ncbi.nlm.nih.gov/pubmed/36103538
http://dx.doi.org/10.1126/sciadv.abo0323